UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549
_________________________

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): October 8, 2007

HMS Holdings Corp.

(Exact Name of Registrant as Specified in Charter)

New York 0-50194 11-3656261
(State or Other Juris- (Commission (IRS Employer
diction of Incorporation File Number) Identification No.)

401 Park Avenue South, New York, New York 10016

(Address of Principal Executive Offices, Zip Code)

Registrant’s telephone number, including area code: (212) 725-7965

Not applicable.

(Former Name or Former Address, if Changed Since Last Report)

     Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

     o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

     o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

     o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

     o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))


TABLE OF CONTENTS

Item 7.01 Regulation FD Disclosure

Item 9.01 Exhibits

Signatures

Exhibit Index

Exhibit 99.1      Press release dated October 8, 2007


Item 7.01 Regulation FD Disclosure

By press release dated October 8, 2007, HMS Holdings Corp. (the "Company") announced it has acquired the business of Peer Review Systems, Inc. d/b/a/ Permedion. A copy of the press release announcing the acquisition is attached as Exhibit 99.1.

Item 9.01 Financial Statements and Exhibits

(c) Exhibits

           The following exhibit relating to Item 7.01 shall be deemed to be furnished, and not filed:

Exhibit No.                                     Description                                              
     
99.1   Press release dated October 8, 2007


SIGNATURES

 

          Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

Date: October 8, 2007

 

By:  /s/ Walter D. Hosp
        Walter D. Hosp
        Chief Financial Officer
        (Principal Financial Officer     
        and Accounting Officer)


INDEX TO EXHIBITS  

Exhibit No.               

   

Description
     

99.1

 

Press release dated October 8, 2007