SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 ----------- FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 March 21, 2001 Date of Report (Date of earliest event reported) APPLERA CORPORATION (Exact Name of Registrant as Specified In Charter) Delaware 1-4389 06-1534213 (State or Other Jurisdiction (Commission (IRS Employer of Incorporation) File No.) Identification No.) 761 Main Avenue Norwalk, Connecticut 06859-0001 (Address of Principal Executive Offices, Including Zip Code) (203) 762-1000 (Registrant's telephone number, including area code) Item 5. Other Items. Attached hereto as Exhibit 99 and incorporated by reference herein is the text of Applera Corporation's press release issued March 21, 2001 regarding an update to the business outlook of its Applied Biosystems Group. Item 7. Financial Statements, Pro Forma Financial Information and Exhibits. (c) Exhibits. The following exhibit is filed with this Report: Exhibit No. Description 99 Press Release issued March 21, 2001. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. APPLERA CORPORATION By: /s/ Dennis L. Winger -------------------------------- Dennis L. Winger Senior Vice President and Chief Financial Officer Dated: March 21, 2001 EXHIBIT INDEX Exhibit No. Description 99 Press Release issued March 21, 2001