FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person *   FINGER ALISON CECILY 2. Date of Event Requiring Statement (Month/Day/Year) 02/14/2018 3. Issuer Name and Ticker or Trading Symbol bluebird bio, Inc. [BLUE] (Last) (First) (Middle) C/O BLUEBIRD BIO, INC., 60 BINNEY STREET 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chief Commercial Officer 5. If Amendment, Date Original Filed(Month/Day/Year) (Street) CAMBRIDGE, MA 02142 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5) Common Stock 834 (1) D   Common Stock 2,750 (2) D   Common Stock 2,063 (3) D   Common Stock 6,250 (4) D   Common Stock 3,942 (5) D Â

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to buy)	  (6)	09/01/2025	Common Stock	25,000	$ 128.86	D	Â
Stock Option (Right to buy)	  (7)	03/01/2026	Common Stock	22,000	$ 50.51	D	Â
Stock Option (Right to buy)	  (8)	02/01/2027	Common Stock	11,000	$ 75.6	D	Â
Stock Option (Right to buy)	  (9)	02/01/2028	Common Stock	25,000	$ 205.25	D	Â

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
FINGER ALISON CECILY C/O BLUEBIRD BIO, INC. 60 BINNEY STREET CAMBRIDGE, MA 02142	Â	Â	  Chief Commercial Officer	Â

Signatures

/s/ Jason F. Cole - Attorney-in-fact		02/20/2018
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Restricted stock units for common stock vest over a three-year period at a rate of 33% on August 17, 2016; 33% on August 17, 2017; and 34% on August 17, 2018.
(2)	Restricted stock units for common stock vest over a four-year period at a rate of 25% on January 1, 2017, 25% on January 1, 2018, 25% on January 1, 2019, and 25% on January 1, 2020.
(3)	Restricted stock units for common stock vest over a four-year period at a rate of 25% on January 4, 2018, 25% on January 4, 2019, 25% on January 4, 2020, and 25% on January 4, 2021.
(4)	Restricted stock units for common stock vest over a four-year period at a rate of 25% on January 4, 2019, 25% on January 4, 2020, 25% on January 4, 2021, and 25% on January 4, 2022.
(5)	648 shares were acquired under the bluebird bio, Inc. employee stock purchase plan.
(6)	This option vests over a four-year period, at a rate of twenty-five percent (25%) on August 17, 2016 and in 36 equal monthly installments thereafter.
(7)	This option vests over a four-year period, at a rate of twenty-five percent (25%) on January 1, 2017, and in 36 equal monthly installments.
(8)	This option vests over a four-year period, at a rate of twenty-five percent (25%) on January 4, 2018 and in 36 equal monthly installments thereafter.
(9)	This option vests over a four-year period, at a rate of twenty-five percent (25%) on January 4, 2019, and in 36 equal monthly installments.

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