UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G (Amendment No. 3)* Under the Securities Exchange Act of 1934 Indevus Pharmaceuticals, Inc. Common Stock, $.001 par value per share (Title of Class of Securities) February 14, 2003 (CUSIP Number: 460573108) December 31, 2002 Date of event which requires filing Check the appropriate box to designate the rule pursuant to which the schedule is filed: |_| Rule 13d-1(b) |X| Rule 13d-1(c) |_| Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be filled for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes to Schedule 13G). Page 1 of 4 -------------------------------------------------------------------------------- CUSIP No. 460573108 13G -------------------------------------------------------------------------------- 1. NAME OF REPORTING PERSONS S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Lindsay A. Rosenwald, M.D. -------------------------------------------------------------------------------- 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) |_| (b) |_| -------------------------------------------------------------------------------- 3. SEC USE ONLY -------------------------------------------------------------------------------- 4. CITIZENSHIP OR PLACE OF ORGANIZATION United States -------------------------------------------------------------------------------- NUMBER OF 5. SOLE VOTING POWER SHARES 2,542,481 ----------------------------------------------------------------- BENEFICIALLY 6. SHARED VOTING POWER OWNED BY None ----------------------------------------------------------------- EACH 7. SOLE DISPOSITIVE POWER REPORTING 2,542,481 ----------------------------------------------------------------- PERSON 8. SHARED DISPOSITIVE POWER WITH None -------------------------------------------------------------------------------- 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,542,481 -------------------------------------------------------------------------------- 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| -------------------------------------------------------------------------------- 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.1% -------------------------------------------------------------------------------- 12. TYPE OF REPORTING PERSON* IN -------------------------------------------------------------------------------- Page 2 of 4 ITEM 1(a). NAME OF ISSUER: Interneuron Pharmaceuticals, Inc.. ITEM 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES: One Ledgemount Center 99 Hayden Avenue Lexington, MA 02421 ITEM 2(a) NAME OF PERSON FILING: Lindsay A. Rosenwald, M.D. ITEM 2(b) ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: Dr. Rosenwald's business address is 787 Seventh Avenue, 48th Floor, New York, New York, 10019. ITEM 2(c). CITIZENSHIP: Dr. Rosenwald is a citizen of the United States of America. ITEM 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, par value $.001 per share. ITEM 2(e). CUSIP NUMBER: 460573108 ITEM 3. |X| CHECK THIS BOX IF THIS STATEMENT IS FILED PURSUANT TO RULE 13d-1(c) ITEM 4. OWNERSHIP For information concerning the ownership of Common Stock of the Company by the Reporting Person, see Items 5 through 9 and 11 of the cover pages to this schedule 13G and footnotes thereto. Item 4 Amount Beneficially Owned: Each of the Reporting Persons may be deemed the beneficial owner of the following number of Shares: Dr. Rosenwald may be deemed the beneficial owner of 3,180,962 Shares, which includes 638,481 shares owned by his wife, Rivki Rosenwald. Dr. Rosenwald disclaims the beneficial ownership of the securities beneficially owned by Rivki Rosenwald except to the extent of his pecuniary interest therein, if any. ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS Not applicable ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON Not applicable Page 3 of 4 ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY Not Applicable ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP Not Applicable ITEM 9. NOTICE OF DISSOLUTION OF GROUP Not Applicable ITEM 10. CERTIFICATION By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in a transaction having that purpose and effect. SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Dated: February 14, 2003 By: /s/ Lindsay A. Rosenwald New York, NY ------------------------------------ Name: Lindsay A. Rosenwald, M.D. Page 4 of 4